Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.58 |
| ▸ | MC5R | P33032 | 2/20 | 0.56 |
| ▸ | MC1R | Q01726 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464473 | 0.92 | MC5R (0.57) | CTSCMC5RMC1RMMP2MMP7 | |
| SCHEMBL12464194 | 0.90 | CTSC (0.67) | CTSC | |
| SCHEMBL12464197 | 0.89 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464359 | 0.89 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464195 | 0.89 | MC5R (0.68) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464361 | 0.86 | CTSC (0.53) | CTSC | |
| SCHEMBL12464476 | 0.84 | MC5R (0.61) | MC5RMC1RMMP2MMP7MMP9 | |
| SCHEMBL12464200 | 0.81 | CTSC (0.56) | CTSC | |
| SCHEMBL12464481 | 0.81 | MC5R (0.59) | MC5RMC1R | |
| SCHEMBL12464202 | 0.81 | MC5R (0.59) | MC5RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |