Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TKT | P29401 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300042 | 0.90 | KCNH2 (0.33) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12464108 | 0.85 | DAO (0.44) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL16622004 | 0.83 | DAO (0.37) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL119494 | 0.83 | CDK2 (0.39) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL13373481 | 0.81 | DAO (0.45) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL12797513 | 0.81 | DAO (0.42) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL1480608 | 0.81 | KCNH2 (0.40) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL4939057 | 0.80 | KCNH2 (0.39) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL1480522 | 0.80 | KCNH2 (0.39) | DAOTRPV4KCNH2MAP4K4PIK3CA | |
| SCHEMBL12079598 | 0.79 | NAMPT (0.36) | DAOKCNH2MAP4K4PIK3CAMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989184-B1 | INSECTICIDAL N-SUBSTITUTED (6-HALOALKYLPYRIDIN-3-YL)ALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2011-07-06 | — | — | EP | disclosed |
| US-7960354-B2 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2011-06-14 | — | — | US | disclosed |
| EP-2057120-B1 | INSECTICIDAL N-SUBSTITUTED (HETEROARYL)CYCLOALKYL SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-05-05 | — | — | EP | disclosed |
| WO-2010022897-A2 | METHOD FOR IMPROVING PLANT GROWTH | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | WO | disclosed |
| US-20090325892-A1 | Synergistic pesticidal mixtures | DOW AGROSCIENCES LLC (US) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325892-A1 | Synergistic pesticidal mixtures | ACHE, DDT, PDE1C | DAO 2015/4885TRPV4 792/4885KCNH2 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.