Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL119494 | 0.86 | CDK2 (0.39) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12464348 | 0.83 | DAO (0.40) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL9610902 | 0.77 | CDK2 (0.37) | CDK2 | |
| SCHEMBL13373481 | 0.77 | DAO (0.45) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL12797513 | 0.77 | DAO (0.42) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL2153112 | 0.77 | CDK2 (0.36) | CDK2 | |
| SCHEMBL1480608 | 0.76 | KCNH2 (0.40) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL4939057 | 0.75 | KCNH2 (0.39) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL1480522 | 0.75 | KCNH2 (0.39) | DAOKCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL14740029 | 0.75 | CDK2 (0.37) | DAOKCNH2MAP4K4PIK3CAMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000180-B2 | Processes for the production of N-substituted sulfoximine pyridine N-oxides | DOW AGROSCIENCES LLC (US) | 2015-04-07 | — | — | US | disclosed |