Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 3/20 | 0.56 |
| ▸ | NPY2R | P49146 | 3/20 | 0.56 |
| ▸ | NPY4R | P50391 | 3/20 | 0.56 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464294 | 0.96 | OPRM1 (0.57) | — | |
| SCHEMBL12464203 | 0.89 | — | — | |
| SCHEMBL12464363 | 0.89 | — | — | |
| SCHEMBL12464361 | 0.88 | CTSC (0.53) | — | |
| SCHEMBL12464362 | 0.88 | — | — | |
| SCHEMBL12464197 | 0.87 | MC5R (0.68) | NPY1RNPY2RNPY4R | |
| SCHEMBL12464195 | 0.87 | MC5R (0.68) | NPY1RNPY2RNPY4R | |
| SCHEMBL12464359 | 0.87 | MC5R (0.68) | NPY1RNPY2RNPY4R | |
| SCHEMBL30291268 | 0.85 | ECE1 (0.69) | NPY1RNPY2RNPY4R | |
| SCHEMBL5558360 | 0.85 | ECE1 (0.69) | NPY1RNPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183358-A1 | METHODS AND COMPOSITIONS FOR DEREPRESSION OF IAP-INHIBITED CASPASE | THE BURNHAM INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |