Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | GFER | P55789 | 2/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724928 | 0.78 | POLB (0.56) | HCAR3RAB9AKDM4EGFERNPC1 | |
| SCHEMBL12730480 | 0.78 | HCAR3 (0.62) | HCAR3RAB9AKDM4EGFERFGFR1 | |
| SCHEMBL23063551 | 0.78 | HCAR3 (0.50) | HCAR3RAB9AKDM4EGFERFGFR1 | |
| SCHEMBL12747298 | 0.77 | HCAR3 (0.49) | HCAR3RAB9AKDM4EGFERNPC1 | |
| SCHEMBL14726018 | 0.77 | HCAR3 (0.49) | HCAR3RAB9AKDM4EGFERNPC1 | |
| SCHEMBL18937427 | 0.74 | FGFR1 (0.51) | HCAR3RAB9AKDM4EGFERFGFR1 | |
| SCHEMBL2270041 | 0.74 | FGFR1 (0.50) | RAB9AKDM4EGFERFGFR1SRC | |
| SCHEMBL4955288 | 0.73 | FGFR1 (0.42) | HCAR3RAB9AKDM4EGFERFGFR1 | |
| SCHEMBL4956118 | 0.73 | FGFR1 (0.42) | HCAR3RAB9AKDM4EGFERFGFR1 | |
| SCHEMBL17563260 | 0.73 | HCAR3 (0.45) | HCAR3RAB9AKDM4EGFERNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| WO-2018075947-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-04-26 | — | — | WO | disclosed |
| US-9416155-B2 | Direct sensing of molecular species by polyfluors on a DNA backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-08-16 | — | — | US | disclosed |
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2012-12-06 | — | — | US | disclosed |
| WO-2011081939-A1 | DIRECT SENSING OF MOLECULAR SPECIES BY POLYFLUORS ON A DNA BACKBONE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309107-A1 | Direct Sensing of Molecular Species by Polyfluors on a DNA Backbone | ERCC4, POLL, POLQ | HCAR3 833/4885RAB9A 4737/4885KDM4E 4349/4885 |
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | HCAR3 3757/4885RAB9A 2724/4885KDM4E 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.