Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13541937 | 0.93 | HPGD (0.61) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12464529 | 0.91 | HPGD (0.54) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12464376 | 0.88 | SCD (0.60) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12464767 | 0.88 | HPGD (0.67) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27728329 | 0.85 | PPARA (0.73) | NPC1MAPTALDH1A1GAAPPARA | |
| SCHEMBL27624385 | 0.85 | PPARA (0.59) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL12464532 | 0.85 | HPGD (0.52) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3454120 | 0.84 | MAPT (0.47) | HPGDNPC1SMN1; SMN2MAPTPPARA | |
| SCHEMBL28449044 | 0.81 | HPGD (0.76) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3454883 | 0.78 | NPC1 (0.48) | HPGDNPC1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184027-A1 | TISSUE SELECTIVE STEAROYL-COA DESATURASE 1 INHIBITORS AND CELL BASED SCREENING ASSAY FOR THEIR IDENTIFICATION | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184027-A1 | TISSUE SELECTIVE STEAROYL-COA DESATURASE 1 INHIBITORS AND CELL BASED SCREENING ASSAY FOR THEIR IDENTIFICATION | SCD, SCD5, CPT1B | HPGD 710/4885NPC1 225/4885SMN1; SMN2 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.