Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454120 | 0.94 | MAPT (0.47) | NPC1SMN1; SMN2RAB9AHPGDMAPT | |
| SCHEMBL3454348 | 0.87 | SCD (0.55) | — | |
| SCHEMBL13541887 | 0.85 | MLYCD (0.43) | NPC1SMN1; SMN2RAB9AUSP2L3MBTL1 | |
| SCHEMBL13541937 | 0.85 | HPGD (0.61) | NPC1SMN1; SMN2RAB9AUSP2L3MBTL1 | |
| SCHEMBL3454603 | 0.83 | RAB9A (0.51) | NPC1SMN1; SMN2RAB9AL3MBTL1TSHR | |
| SCHEMBL3447237 | 0.83 | SCD (0.56) | NPC1SMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL3455792 | 0.78 | TAAR1 (0.48) | NPC1RAB9AHPGDKDM4EALDH1A1 | |
| SCHEMBL12464577 | 0.78 | SCD (0.51) | SMN1; SMN2RAB9ATSHRHPGDPOLB | |
| SCHEMBL12464375 | 0.78 | HPGD (0.64) | NPC1SMN1; SMN2HPGDMEN1GAA | |
| SCHEMBL3454860 | 0.78 | MAOB (0.52) | NPC1L3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | claimed |