Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | CPB1 | P15086 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 12/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464648 | 0.96 | CPB1 (0.52) | CNR2CPB1NR1H4SMN1; SMN2MAPT | |
| SCHEMBL2157810 | 0.93 | CPB1 (0.57) | CNR2CPB1NR1H4SMN1; SMN2MAPT | |
| SCHEMBL2157556 | 0.89 | CPB1 (0.59) | CPB1NR1H4SMN1; SMN2MAPTKMT2A | |
| SCHEMBL12464430 | 0.88 | CPB1 (0.47) | CNR2CPB1NR1H4SMN1; SMN2LMNA | |
| SCHEMBL12464236 | 0.86 | CPB1 (0.51) | CNR2CPB1NR1H4MAPTKMT2A | |
| SCHEMBL12464574 | 0.83 | NR1H4 (0.49) | CPB1NR1H4MAPTKMT2ALMNA | |
| SCHEMBL12464234 | 0.83 | CPB1 (0.48) | CPB1NR1H4MAPTKMT2ALMNA | |
| SCHEMBL2157590 | 0.83 | CPB1 (0.44) | CNR2CPB1NR1H4MAPTKMT2A | |
| SCHEMBL2158429 | 0.81 | LTB4R2 (0.47) | CNR2MAPTKMT2ALMNACNR1 | |
| SCHEMBL2157917 | 0.81 | HTT (0.43) | CNR2CPB1NR1H4SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |