Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12464387 | 0.96 | CNR2 (0.51) | CPB1CNR2CNR1HTTNR1H4 | |
| SCHEMBL2157556 | 0.93 | CPB1 (0.59) | CPB1HTTNR1H4KMT2AMAPT | |
| SCHEMBL12464236 | 0.90 | CPB1 (0.51) | CPB1CNR2CNR1HTTNR1H4 | |
| SCHEMBL2157810 | 0.88 | CPB1 (0.57) | CPB1CNR2CNR1HTTNR1H4 | |
| SCHEMBL12464574 | 0.87 | NR1H4 (0.49) | CPB1HTTNR1H4KMT2AMAPT | |
| SCHEMBL12464234 | 0.87 | CPB1 (0.48) | CPB1HTTNR1H4KMT2AMAPT | |
| SCHEMBL2158429 | 0.85 | LTB4R2 (0.47) | CNR2CNR1HTTKMT2AMAPT | |
| SCHEMBL12464430 | 0.83 | CPB1 (0.47) | CPB1CNR2CNR1NR1H4HDAC6 | |
| SCHEMBL2157845 | 0.82 | LTB4R2 (0.48) | CNR1NR1H4KMT2AMAPT | |
| SCHEMBL12464657 | 0.80 | LTB4R2 (0.50) | CNR2CNR1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |