Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142514 | 0.85 | PTGS1 (0.51) | ALDH1A1SMN1; SMN2PDE3BPDE3AKIF11 | |
| SCHEMBL6852399 | 0.83 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2KIF11KDM4EPTGS2 | |
| SCHEMBL15341612 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KIF11PTGS1KDM4E | |
| SCHEMBL257774 | 0.81 | MEN1 (0.46) | ALDH1A1SMN1; SMN2PTGS1KDM4EMEN1 | |
| SCHEMBL14879562 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KIF11PTGS1KDM4E | |
| SCHEMBL14879527 | 0.78 | HSD17B10 (0.52) | ALDH1A1SMN1; SMN2KIF11PTGS1KDM4E | |
| SCHEMBL4892898 | 0.78 | ALDH5A1 (0.52) | ALDH1A1SMN1; SMN2PDE3BPDE3AKIF11 | |
| SCHEMBL416643 | 0.77 | PTGS1 (0.51) | ALDH1A1KIF11PTGS1KDM4EMEN1 | |
| SCHEMBL31120808 | 0.77 | PTGS1 (0.51) | ALDH1A1KIF11PTGS1KDM4EMEN1 | |
| SCHEMBL6854203 | 0.76 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KIF11KDM4EPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337718-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110180756-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110180756-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | LASP1, VCL, NLK | ALDH1A1 3939/4885SMN1; SMN2 2261/4885PDE3B 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.