Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158037 | 0.86 | CYP3A4 (0.40) | GAA | |
| SCHEMBL14950511 | 0.75 | CYP1A2 (0.40) | MAPT | |
| SCHEMBL2158600 | 0.74 | HSD17B1 (0.46) | — | |
| SCHEMBL3816559 | 0.73 | KMT2A (0.34) | — | |
| SCHEMBL2878956 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL2158446 | 0.72 | KDM4E (0.42) | MAPTRAB9A | |
| SCHEMBL3807323 | 0.71 | NPC1 (0.49) | RAB9A | |
| SCHEMBL2157942 | 0.70 | — | — | |
| SCHEMBL12357684 | 0.68 | HSD17B1 (0.42) | — | |
| SCHEMBL2157628 | 0.68 | KDM4E (0.40) | ALDH1A1MAPTHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |