Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MANBA | O00462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GLB1 | P16278 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146568 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL19129777 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL19129720 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL2159235 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL4131205 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL23288111 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL4141870 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL12396147 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL19146746 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 | |
| SCHEMBL13106543 | 0.84 | LMNA (0.47) | HIF1AMANBALMNATHRBGLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | THOMAS JEFFERSON UNIVERSITY | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184019-A1 | Long chain N-Alkyl compounds and oxa-derivatives thereof | OXA1L, OTC, PAICS | HIF1A 3649/4885MANBA 4339/4885LMNA 534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.