Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27989653 | 0.81 | ALDH1A1 (0.52) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL21969580 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL18543085 | 0.79 | ALDH1A1 (0.50) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL14519094 | 0.79 | MAPT (0.46) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL15694555 | 0.78 | MMP2 (0.63) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL29593727 | 0.78 | MAPT (0.57) | MAPTGAAALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL6299937 | 0.78 | MAPT (0.57) | MAPTGAAALDH1A1ALOX15SMN1; SMN2 | |
| Anthranilic Acid SCHEMBL9615435 | 0.77 | ALDH1A1 (0.62) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL30762855 | 0.77 | ALDH1A1 (0.48) | MAPTGAAALDH1A1L3MBTL1ALOX15 | |
| SCHEMBL345557 | 0.77 | ALDH1A1 (0.48) | MAPTGAAALDH1A1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777218-B1 | Process for the preparation of 4-phenoxy quinoline derivatives | EISAI R&D MAN CO LTD (JP) | 2008-12-31 | — | — | EP | disclosed |