Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157485 | 0.91 | NR1I2 (0.39) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL12464253 | 0.88 | KDM4E (0.37) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL12464670 | 0.85 | KDM4E (0.38) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL12464440 | 0.83 | MKNK1 (0.40) | KDM4EHTTATM | |
| SCHEMBL17635079 | 0.80 | KDM4E (0.42) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL2878321 | 0.80 | KDM4E (0.42) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL2244516 | 0.80 | CYP2E1 (0.40) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL2157768 | 0.79 | NR1I2 (0.38) | PTPRFPTPN1KDM4EHTTATM | |
| SCHEMBL3815104 | 0.78 | KDM4E (0.36) | KDM4EHTTATM | |
| SCHEMBL102105 | 0.78 | KDM4E (0.39) | PTPRFPTPN1KDM4EHTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985769-B2 | Compounds and methods for the treatment or prevention of Flavivirus infections | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-07-26 | — | — | US | disclosed |