⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101985 | 0.75 | — | — | |
| SCHEMBL19413111 | 0.71 | — | — | |
| SCHEMBL17429857 | 0.67 | CYP19A1 (0.37) | — | |
| SCHEMBL8507646 | 0.67 | ATM (0.37) | — | |
| SCHEMBL10288808 | 0.65 | — | — | |
| SCHEMBL12469850 | 0.65 | GOT1 (0.34) | — | |
| SCHEMBL22313680 | 0.62 | — | — | |
| SCHEMBL22607455 | 0.62 | EGFR (0.40) | — | |
| SCHEMBL10042014 | 0.61 | HSP90AA1 (0.38) | — | |
| SCHEMBL18971809 | 0.61 | ESR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110183947-A1 | ALPHA-KETO HETEROCYCLES AS FAAH INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2011-07-28 | — | — | US | disclosed |
| US-20090270421-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-10-29 | — | — | US | disclosed |