Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.80 |
| ▸ | HRH1 | P35367 | 3/20 | 0.80 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.80 |
| ▸ | CNR1 | P21554 | 2/20 | 0.80 |
| ▸ | GHSR | Q92847 | 2/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.80 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.74 |
| ▸ | DRD3 | P35462 | 3/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.74 |
| ▸ | DRD1 | P21728 | 2/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611802 | 0.97 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL588111 | 0.97 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL588110 | 0.97 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588103 | 0.95 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL587709 | 0.95 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588128 | 0.95 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL9720751 | 0.93 | KCNH2 (0.71) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL1569388 | 0.89 | KCNH2 (0.70) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Buclizine SCHEMBL22171621 | 0.89 | KCNH2 (1.00) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Buclizine SCHEMBL123752 | 0.89 | KCNH2 (1.00) | KCNH2HRH1OPRK1ADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8350031-B2 | Processes for the synthesis of levocetirizine and intermediates for use therein | CIPLA LIMITED (IN) | 2013-01-08 | — | — | US | disclosed |
| US-20110184174-A1 | Processes for the Synthesis of Levocetirizine and Intermediates for Use Therein | CIPLA LIMITED (IN) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184174-A1 | Processes for the Synthesis of Levocetirizine and Intermediates for Use Therein | CYP3A5, CYP4A11, IL5 | KCNH2 1377/4885HRH1 82/4885OPRK1 625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.