Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.71 |
| ▸ | HRH1 | P35367 | 3/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | CNR1 | P21554 | 2/20 | 0.71 |
| ▸ | GHSR | Q92847 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.66 |
| ▸ | DRD3 | P35462 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | DRD2 | P14416 | 2/20 | 0.66 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.66 |
| ▸ | DRD1 | P21728 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720705 | 0.94 | KCNH2 (0.62) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Belarizine SCHEMBL2108057 | 0.93 | ATM (0.73) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL12464946 | 0.93 | KCNH2 (0.80) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL3611802 | 0.90 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL588111 | 0.90 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL588110 | 0.90 | KCNH2 (0.78) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588103 | 0.89 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL587709 | 0.89 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| Hydrochloric Acid SCHEMBL588128 | 0.89 | LMNA (0.79) | KCNH2HRH1OPRK1ADORA3CNR1 | |
| SCHEMBL8744969 | 0.86 | ATM (0.67) | KCNH2HRH1OPRK1ADORA3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142052-A | Cationic effect-driven carbinol/amine reaction | LABORATOIRES SYNTEX (FR) | 1992-08-25 | — | — | US | disclosed |