Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1244748 | 0.91 | KDM4E (0.56) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL28435833 | 0.84 | RAB9A (0.65) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL28435835 | 0.84 | RAB9A (0.65) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL1246644 | 0.81 | MAPT (0.54) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL4713464 | 0.79 | NPC1 (0.52) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL4713462 | 0.79 | NPC1 (0.52) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL10401659 | 0.78 | GRM4 (0.57) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL10401660 | 0.78 | GRM4 (0.57) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL9170782 | 0.78 | RAB9A (0.89) | KDM4EMAPTRAB9ALMNANPC1 | |
| SCHEMBL9170780 | 0.78 | RAB9A (0.89) | KDM4EMAPTRAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | claimed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | claimed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | claimed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | claimed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | claimed |
| EP-2459734-B1 | NOVEL PEPTIDASE SUBSTRATES | BIOMERIEUX SA (FR) | 2014-10-08 | — | — | EP | disclosed |
| US-8592174-B2 | Peptidase substrates | bioMérieux, S.A. (FR) | 2013-11-26 | — | — | US | disclosed |
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122135-A1 | Novel Peptidase Substrates | bioMerieux, SA (FR) | 2012-05-17 | — | — | US | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122135-A1 | Novel Peptidase Substrates | CPN1, CTRL, ANPEP | KDM4E 3975/4885MAPT 4874/4885RAB9A 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.