Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.85 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | RORB | Q92753 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465747 | 0.92 | RORC (1.00) | RORCNR1I2RORB | |
| SCHEMBL12465756 | 0.92 | RORC (1.00) | RORCNR1I2RORB | |
| SCHEMBL12467550 | 0.91 | RORC (1.00) | RORCNR1I2RORB | |
| SCHEMBL12467518 | 0.88 | RORC (1.00) | RORCNR1I2RORB | |
| SCHEMBL12467562 | 0.88 | RORC (0.84) | RORCRORB | |
| SCHEMBL12468543 | 0.87 | RORC (0.87) | RORCRORB | |
| SCHEMBL12467544 | 0.86 | RORC (0.78) | RORC | |
| SCHEMBL12465929 | 0.86 | RORC (1.00) | RORCNR1I2RORB | |
| SCHEMBL12465697 | 0.86 | RORC (0.82) | RORCRORB | |
| SCHEMBL12467507 | 0.85 | RORC (0.85) | RORCNR1I2RORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100732-A1 | RETINOID-RELATED ORPHAN RECEPTOR GAMMA MODULATORS, COMPOSITION CONTAINING THEM AND USES THEREOF | GLAXO GROUP LIMITED (GB) | 2012-08-02 | — | — | WO | disclosed |