Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465973 | 0.88 | MAPT (0.40) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12465743 | 0.88 | MAPT (0.47) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12465889 | 0.83 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL15451661 | 0.78 | LPAR1 (0.63) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL27931670 | 0.78 | MAPT (0.39) | MAPTBRD4POLBTP53CA2 | |
| SCHEMBL12467498 | 0.75 | MAPT (0.52) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL4037272 | 0.75 | MAPT (0.54) | MAPTKDM4ELPAR1LPAR3POLB | |
| SCHEMBL2761636 | 0.74 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3POLB | |
| SCHEMBL4035675 | 0.73 | MAPT (0.67) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12465689 | 0.73 | MAPT (0.51) | MAPTKDM4ELPAR1LPAR3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |