Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465702 | 0.88 | MAPT (0.44) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12465743 | 0.86 | MAPT (0.47) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12465889 | 0.81 | MAPT (0.53) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL27931580 | 0.79 | KIT (0.39) | KIT | |
| SCHEMBL15451657 | 0.79 | LPAR1 (0.61) | MAPTKDM4ELPAR1LPAR3 | |
| SCHEMBL12466023 | 0.77 | KIT (0.41) | MAPTKDM4EKITBRD4 | |
| SCHEMBL4034870 | 0.76 | MAPT (0.52) | MAPTKDM4ELPAR1LPAR3 | |
| SCHEMBL4037473 | 0.74 | MAPT (0.51) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL12467498 | 0.73 | MAPT (0.52) | MAPTKDM4ELPAR1LPAR3BRD4 | |
| SCHEMBL6003 | 0.73 | LPAR1 (0.54) | MAPTKDM4ELPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |