Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 13/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | CDK7 | P50613 | 1/20 | 0.44 |
| ▸ | CCNH | P51946 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12465926 | 1.00 | CCNT1 (0.59) | CCNT1KDM1ACDK9CSNK1A1CSNK1D | |
| SCHEMBL12466465 | 0.81 | CCNT1 (0.50) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL12466469 | 0.81 | CCNT1 (0.50) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL12465924 | 0.78 | CDK9 (0.42) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL12466160 | 0.78 | CCNT1 (0.52) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL12466162 | 0.78 | CCNT1 (0.52) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E | |
| SCHEMBL1192916 | 0.74 | CCNT1 (1.00) | CCNT1CDK9CCNK | |
| SCHEMBL1191738 | 0.73 | CCNT1 (0.70) | CCNT1 | |
| SCHEMBL1191736 | 0.73 | CCNT1 (0.70) | CCNT1 | |
| SCHEMBL31334729 | 0.73 | CCNT1 (0.53) | CCNT1CDK9CSNK1A1CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101065-A2 | PYRIMIDINE BIARYL AMINE COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |