Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMURF2 | Q9HAU4 | 1/20 | 0.37 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466023 | 0.86 | KIT (0.41) | MAPTKDM4ECYP17A1P2RY1HAVCR2 | |
| SCHEMBL15451595 | 0.81 | LPAR1 (0.57) | MAPTKDM4EDPP4DPP7LPAR1 | |
| SCHEMBL12465889 | 0.81 | MAPT (0.53) | MAPTKDM4EHPGDLPAR1LPAR3 | |
| SCHEMBL27931724 | 0.79 | CYP17A1 (0.42) | MAPTCYP17A1P2RY1MEN1POLB | |
| SCHEMBL12465743 | 0.77 | MAPT (0.47) | MAPTKDM4EPOLBLPAR1LPAR3 | |
| SCHEMBL15437811 | 0.74 | DPP4 (0.38) | CYP17A1DPP4DPP7GAAHPGD | |
| SCHEMBL15451652 | 0.73 | LPAR1 (0.55) | MAPTKDM4EP2RY1LPAR1LPAR3 | |
| SCHEMBL15451649 | 0.73 | LPAR1 (0.55) | MAPTKDM4EP2RY1LPAR1LPAR3 | |
| SCHEMBL12465702 | 0.72 | MAPT (0.44) | MAPTKDM4EPOLBLPAR1LPAR3 | |
| SCHEMBL12465973 | 0.70 | MAPT (0.40) | MAPTKDM4ELPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | claimed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |