SCHEMBL1246689

SCHEMBL1246689

CCOC(=O)CC(C(=O)OCC)C1CC2CCC1C2

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
EPHX2 P34913 1/20 0.47
CYP2D6 P10635 1/20 0.47
HPGD P15428 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GRM1 Q13255 2/20 0.36
NPC1 O15118 1/20 0.34
CYP3A4 P08684 2/20 0.33
ALOX15 P16050 2/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CHRM1 P11229 1/20 0.33
ADORA1 P30542 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2456829 0.83 ALDH1A1 (0.43) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL2454932 0.82 ALDH1A1 (0.39) ALDH1A1EPHX2CYP2D6HPGDLMNA
SCHEMBL2999547 0.77 ALDH1A1 (0.50) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL14576219 0.77 ALDH1A1 (0.43) ALDH1A1EPHX2CYP2D6HPGDLMNA
SCHEMBL26632843 0.76 ALDH1A1 (0.49) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL1245653 0.74 CYP2D6 (0.56) ALDH1A1CYP2D6LMNACYP3A4ALOX15
SCHEMBL29036101 0.73 CYP2D6 (0.50) ALDH1A1EPHX2CYP2D6HPGDCYP3A4
SCHEMBL27532523 0.73 CYP2D6 (0.56) ALDH1A1CYP2D6CYP3A4ALOX15TSHR
SCHEMBL2999551 0.72 ALDH1A1 (0.46) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL27791143 0.72 CYP2D6 (0.52) ALDH1A1CYP2D6NPC1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-119331132-A Catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
EP-3765566-B1 POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-06 EP disclosed
US-11807744-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-11-07 US disclosed
CN-116997578-A Prepolymerized catalyst component for olefin polymerization 巴塞尔聚烯烃意大利有限公司 2023-11-03 CN disclosed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN disclosed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP disclosed
US-20050032633-A1 Propylene polymers BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2005-02-10 US disclosed
US-20050014631-A1 Catalyst system for the polymerization of olefins BASELL POLYOLEFINE ITALIA S.P.A. (IT) 2005-01-20 US disclosed
US-6825309-B2 COMPRISING MG, TI, HALOGEN AND AT LEAST TWO ELECTRON DONOR COMPOUNDS: A) NON-EXTRACTABLE ESTERS OF 2,3-DIALKYLSUCCINIC ACIDS WHICH ARE NOT EXTRACTABLE AND B) AN EXTRACTABLE ELECTRON DONOR, SUCH AS DIALKYL PHTHALATES BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-30 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
US-20030060581-A1 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-03-27 US disclosed
EP-1272533-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.p.A. (IT) 2003-01-08 EP disclosed
WO-2002030998-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2002-04-18 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed