SCHEMBL2454932

SCHEMBL2454932

CC(C)(C)COC(=O)CC(C(=O)OCC(C)(C)C)C1CC2CCC1C2

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
EPHX2 P34913 1/20 0.36
HPGD P15428 3/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.32
CYP2D6 P10635 1/20 0.31
KMT2A Q03164 2/20 0.30
MEN1 O00255 1/20 0.30
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246689 0.82 ALDH1A1 (0.53) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL2456829 0.80 ALDH1A1 (0.43) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL28342842 0.76 NPSR1 (0.42) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL2453465 0.76 CYP2D6 (0.36) CYP2D6
SCHEMBL21866693 0.75 CYP2D6 (0.37) CYP2D6
SCHEMBL26909736 0.74 CYP2D6 (0.34) CYP2D6
SCHEMBL2455026 0.73 CYP2D6 (0.40) ALDH1A1EPHX2CYP2D6KMT2AMEN1
SCHEMBL21866690 0.69 CYP2D6 (0.33) CYP2D6
SCHEMBL5277464 0.68 HPGD (0.40) ALDH1A1EPHX2HPGDLMNASMN1; SMN2
SCHEMBL4808462 0.68 ALDH1A1 (0.39) ALDH1A1EPHX2HPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
EP-4323415-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2024-02-21 EP disclosed
EP-3765566-B1 POLYPROPYLENE COMPOSITION AND MOLDED ARTICLE BASELL POLIOLEFINE ITALIA SRL (IT) 2023-12-06 EP disclosed
US-11807744-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2023-11-07 US disclosed
CN-111712541-B Polypropylene composition and molded article 巴塞尔聚烯烃意大利有限公司(IT) 2023-01-13 CN disclosed
WO-2022218869-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-10-20 WO disclosed
CN-114716591-A Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2022-07-08 CN disclosed
US-11339280-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-24 US disclosed
US-11319431-B2 Polypropylene composition and molded article BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2022-05-03 US disclosed
US-20140046010-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.I. (IT) 2014-02-13 US disclosed
EP-2542592-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.R.L. (IT) 2013-01-09 EP disclosed
US-20120316300-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-12-13 US disclosed
WO-2012139897-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2012-10-18 WO disclosed
WO-2011107371-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2011-09-09 WO disclosed
US-20100249330-A1 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2010-09-30 US disclosed
EP-2201049-A2 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS Basell Poliolefine Italia S.r.l. (IT) 2010-06-30 EP disclosed
WO-2009050045-A2 PROCESS FOR THE PREPARATION OF HIGH FLUIDITY PROPYLENE POLYMERS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2009-04-23 WO disclosed
US-7202314-B2 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2007-04-10 US disclosed
US-20060105906-A1 Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2006-05-18 US disclosed