SCHEMBL1246719

SCHEMBL1246719

CCOC(=O)CC(CC(C)C)(CC(C)C)C(=O)OCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.49
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 1/20 0.38
PKM P14618 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GSK3A P49840 1/20 0.33
GSK3B P49841 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1244531 0.93 MMP8 (0.46) MMP8GAAMGAMSIMGAM2
SCHEMBL28963018 0.89 MMP8 (0.46) MMP8GAAMGAMSIMGAM2
SCHEMBL28138996 0.89 MMP8 (0.50) MMP8GAAMGAMSIMGAM2
SCHEMBL1246409 0.89 MMP8 (0.43) MMP8GAAMGAMSIMGAM2
SCHEMBL27512516 0.85 MMP8 (0.41) MMP8GAAMGAMSIMGAM2
SCHEMBL27512517 0.85 MMP8 (0.49) MMP8GAAMGAMSIMGAM2
SCHEMBL14417059 0.82 MMP8 (0.53) MMP8GAAMGAMSIMGAM2
SCHEMBL235487 0.82 MMP8 (0.46) MMP8GAAMGAMSIMGAM2
SCHEMBL2454119 0.81 TSHR (0.41) MMP8GAAALDH1A1MEN1KMT2A
SCHEMBL14743485 0.81 MMP8 (0.49) MMP8GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430735-A Catalyst component for propylene polymerization, preparation method thereof, catalyst and application 中国石油化工股份有限公司 2024-01-23 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-104558287-B Catalyst component for olefin and catalyst 中国石油化工股份有限公司 2017-03-01 CN claimed
CN-119630709-A Strain hardening reinforced polypropylene composition and method for producing the same 埃克森美孚化学专利公司 2025-03-14 CN disclosed
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
CN-119331132-A Catalyst component for olefin polymerization, olefin polymerization catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
CN-119331139-A Catalyst component for olefin polymerization, catalyst and application thereof 中国石油天然气股份有限公司 2025-01-21 CN disclosed
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3559113-B1 MASTERBATCH COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2024-06-12 EP disclosed
CN-114716591-B Catalyst component for propylene polymerization, preparation method and application thereof 任丘市利和科技发展有限公司 2024-05-28 CN disclosed
CN-117924548-A Catalyst component for olefin polymerization, preparation method, catalyst system and olefin polymerization method 中国石油化工股份有限公司 2024-04-26 CN disclosed
US-6825309-B2 COMPRISING MG, TI, HALOGEN AND AT LEAST TWO ELECTRON DONOR COMPOUNDS: A) NON-EXTRACTABLE ESTERS OF 2,3-DIALKYLSUCCINIC ACIDS WHICH ARE NOT EXTRACTABLE AND B) AN EXTRACTABLE ELECTRON DONOR, SUCH AS DIALKYL PHTHALATES BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-30 US disclosed
US-6818583-B1 HIGH YIELDS AND HIGH ISOTACTIC INDEX; COMPRISING MG, TI, HALOGEN AND A SUCCINATE ELECTRON DONOR BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-11-16 US disclosed
CN-1545525-A Catalyst system for olefin polymerization ��������ϩ����������޹�˾ 2004-11-10 CN disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
WO-2003076479-A1 PROCESS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-09-18 WO disclosed
US-20030060581-A1 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-03-27 US disclosed
EP-1272533-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.p.A. (IT) 2003-01-08 EP disclosed
WO-2002030998-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2002-04-18 WO disclosed