SCHEMBL235487

SCHEMBL235487

CCOC(=O)CCC(CC(C)C)(CC(C)C)C(=O)OCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.46
CYP4F2 P78329 3/20 0.41
CYP4A11 Q02928 3/20 0.41
CYP1A2 P05177 1/20 0.39
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
TRPA1 O75762 1/20 0.35
ALDH1A1 P00352 1/20 0.35
KMT2A Q03164 3/20 0.35
MEN1 O00255 1/20 0.35
THRB P10828 1/20 0.34
PKM P14618 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.33
NR1I2 O75469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1246719 0.82 MMP8 (0.49) MMP8CYP4F2CYP4A11CYP1A2GAA
SCHEMBL11707258 0.82 CYP4F2 (0.59) CYP4F2CYP4A11CYP1A2GAAMGAM
SCHEMBL14417059 0.80 MMP8 (0.53) MMP8CYP4F2CYP4A11GAAMGAM
SCHEMBL1244531 0.79 MMP8 (0.46) MMP8CYP4F2CYP4A11CYP1A2GAA
SCHEMBL1246409 0.79 MMP8 (0.43) MMP8CYP4F2CYP4A11GAAMGAM
SCHEMBL18050398 0.78 MMP8 (0.45) MMP8CYP4F2CYP4A11L3MBTL1ALDH1A1
SCHEMBL18050448 0.77 MMP8 (0.47) MMP8CYP4F2CYP4A11GAAMGAM
SCHEMBL28138996 0.76 MMP8 (0.50) MMP8CYP4F2CYP4A11GAAMGAM
SCHEMBL18050380 0.76 MMP8 (0.43) MMP8CYP4F2CYP4A11L3MBTL1ALDH1A1
SCHEMBL7860159 0.75 MEN1 (0.57) CYP4F2CYP4A11CYP1A2GAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed