Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15689239 | 0.86 | NPC1 (0.54) | RAB9ANPC1ABL1GRM1SMN1; SMN2 | |
| SCHEMBL12468521 | 0.85 | GRM1 (0.53) | RAB9ANPC1GRM1SMN1; SMN2KDM4E | |
| SCHEMBL15849768 | 0.84 | SCN9A (0.58) | RAB9ANPC1GRM1SMN1; SMN2KDM4E | |
| SCHEMBL17183405 | 0.84 | RAB9A (0.52) | RAB9ANPC1ABL1GRM1SMN1; SMN2 | |
| SCHEMBL13078667 | 0.83 | ABL1 (0.61) | RAB9ANPC1ABL1GRM1SMN1; SMN2 | |
| SCHEMBL12468471 | 0.82 | MEN1 (0.58) | RAB9ANPC1GRM1SMN1; SMN2KDM4E | |
| SCHEMBL12469470 | 0.82 | SCN9A (0.48) | RAB9ANPC1ABL1SMN1; SMN2KDM4E | |
| SCHEMBL15689210 | 0.82 | RAB9A (0.50) | RAB9ANPC1ABL1GRM1SMN1; SMN2 | |
| SCHEMBL3613493 | 0.81 | RAB9A (0.63) | RAB9ANPC1ABL1SMN1; SMN2KDM4E | |
| SCHEMBL15689178 | 0.81 | RAB9A (0.49) | RAB9ANPC1ABL1GRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SERPINB1, CTSC, HPN | RAB9A 2089/4885NPC1 309/4885ABL1 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.