Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20388038 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL1248173 | 0.75 | TDP1 (0.44) | TSHRHTTTDP1KMT2APOLB | |
| SCHEMBL14680472 | 0.73 | CYP3A4 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4KMT2A | |
| SCHEMBL195265 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HTTKMT2APKMMAPT | |
| SCHEMBL902711 | 0.70 | NPSR1 (0.44) | ALDH1A1HSD17B10TSHRCYP3A4TDP1 | |
| SCHEMBL537959 | 0.70 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL8005268 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL9225008 | 0.70 | ALDH1A1 (0.65) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL12597837 | 0.69 | L3MBTL1 (0.52) | ALDH1A1HSD17B10TSHRCYP3A4HTT | |
| SCHEMBL11238708 | 0.69 | POLB (0.31) | POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462239-A1 | FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN | Roche Diagnostics GmbH (DE) | 2012-06-13 | — | — | EP | claimed |
| WO-2011015325-A1 | FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN | ROCHE DIAGNOSTICS GMBH (DE) | 2011-02-10 | — | — | WO | claimed |
| EP-0354441-B1 | Method for the colorimetric determination of analyte using enzymatic oxydation | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-17 | — | — | EP | claimed |
| WO-2021039611-A1 | METHOD FOR MEASURING PENTOSIDINE AND MEASUREMENT KIT | キッコーマン株式会社 | 2021-03-04 | — | — | WO | disclosed |
| EP-2462239-A1 | FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN | Roche Diagnostics GmbH (DE) | 2012-06-13 | — | — | EP | disclosed |
| EP-2462223-A2 | FRUCTOSYL AMINO ACID OXIDASE | Roche Diagnostics GmbH (DE) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011015325-A1 | FRUCTOSYL PEPTIDYL OXIDASE AND SENSOR FOR ASSAYING A GLYCATED PROTEIN | ROCHE DIAGNOSTICS GMBH (DE) | 2011-02-10 | — | — | WO | disclosed |
| WO-2011015326-A2 | FRUCTOSYL AMINO ACID OXIDASE | ROCHE DIAGNOSTICS GMBH (DE) | 2011-02-10 | — | — | WO | disclosed |
| EP-0354441-B1 | Method for the colorimetric determination of analyte using enzymatic oxydation | BOEHRINGER MANNHEIM GMBH (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-5334508-A | A mixture reagent consisting of an oxidoreductase enzyme, an aromatic nitroso or a oxime compound and a couplers; free of reducing catalysts, side-effect reduction | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5318882-A | Nitrosodiphenylamine compounds render dyes lightfast | TAIYO YUDEN CO., LTD. (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5206147-A | COLORIMETRIC ASSAY BY ENZYMATIC OXIDATION IN THE PRESENCE OF AN AROMATIC NITROSO OR OXIME COMPOUND | BOEHRINGER MANNHEIM GMBH (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0354441-A2 | Method for the colorimetric determination of analyte using enzymatic oxydation | Roche Diagnostics GmbH (DE) | 1990-02-14 | — | — | EP | disclosed |