Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279861 | 0.90 | TACR1 (0.44) | SLC6A9SCN9A | |
| SCHEMBL1280207 | 0.90 | TACR1 (0.44) | SLC6A9SCN9A | |
| SCHEMBL16380488 | 0.90 | TACR1 (0.44) | SLC6A9SCN9A | |
| SCHEMBL1279865 | 0.90 | TACR1 (0.44) | SLC6A9SCN9A | |
| SCHEMBL1280205 | 0.90 | TACR1 (0.44) | SLC6A9SCN9A | |
| SCHEMBL15428476 | 0.80 | SLC6A4 (0.41) | CCR5SLC6A4SLC6A2LIPEEPHX2 | |
| SCHEMBL3967738 | 0.74 | PPARG (0.62) | PPARGPPARASLC6A4SLC6A2SLC6A9 | |
| SCHEMBL1689415 | 0.73 | MMP13 (0.43) | LIPEEPHX2 | |
| SCHEMBL14837995 | 0.73 | MMP13 (0.43) | LIPEEPHX2 | |
| SCHEMBL9108211 | 0.73 | MMP13 (0.45) | LIPEEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627630-A1 | SEROTONIN REUPTAKE INHIBITORS | Theravance, Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012051103-A1 | SEROTONIN REUPTAKE INHIBITORS | THERAVANCE, INC. (US) | 2012-04-19 | — | — | WO | disclosed |