Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9107358 | 0.89 | MMP13 (0.45) | ALDH1A1EPHX2 | |
| SCHEMBL9107353 | 0.89 | MMP13 (0.45) | ALDH1A1EPHX2 | |
| SCHEMBL9280632 | 0.87 | LIPC (0.40) | SLC6A4HRH3SMYD3EPHX2LIPE | |
| SCHEMBL12468333 | 0.80 | PPARG (0.39) | SLC6A4HRH3RAB9ASLC6A2ALDH1A1 | |
| SCHEMBL9108211 | 0.78 | MMP13 (0.45) | ALDH1A1EPHX2LIPE | |
| SCHEMBL9108220 | 0.78 | MMP13 (0.45) | ALDH1A1EPHX2LIPE | |
| SCHEMBL9110045 | 0.77 | DPP4 (0.45) | EPHX2 | |
| SCHEMBL9110055 | 0.77 | DPP4 (0.45) | EPHX2 | |
| SCHEMBL14837995 | 0.76 | MMP13 (0.43) | EPHX2LIPE | |
| SCHEMBL9281151 | 0.76 | LIPC (0.39) | SLC6A4LMNAHRH3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637568-B2 | Serotonin reuptake inhibitors | THERAVANCE, INC. (US) | 2014-01-28 | — | — | US | disclosed |