Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12553864 | 0.80 | SMN1; SMN2 (0.54) | HSD17B10SMN1; SMN2ALOX15TSHRALDH1A1 | |
| SCHEMBL6446184 | 0.80 | GLA (0.40) | KDM4EHSD17B10SMN1; SMN2ALDH1A1GLA | |
| SCHEMBL12553863 | 0.78 | SMN1; SMN2 (0.57) | HSD17B10SMN1; SMN2ALOX15TSHRALDH1A1 | |
| SCHEMBL7395028 | 0.76 | SMN1; SMN2 (0.46) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL11250525 | 0.75 | USP2 (0.41) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL1246843 | 0.71 | KDM4E (0.36) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL18193869 | 0.70 | USP2 (0.37) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| Dimethylformamide SCHEMBL1788685 | 0.69 | GLA (0.42) | KDM4ESMN1; SMN2TSHRALDH1A1USP2 | |
| SCHEMBL19243880 | 0.69 | L3MBTL1 (0.47) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR | |
| SCHEMBL8896209 | 0.68 | USP2 (0.35) | KDM4EHSD17B10SMN1; SMN2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | claimed |
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2011-06-16 | — | — | US | disclosed |
| WO-2011014520-A2 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | QSOX1, PRDX2, NQO2 | KDM4E 2076/4885HSD17B10 2876/4885SMN1; SMN2 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.