Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849614 | 0.91 | CYP1A2 (0.39) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8133581 | 0.83 | KDM4E (0.51) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3374484 | 0.83 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL745082 | 0.81 | CYP1A2 (0.43) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL743993 | 0.81 | CYP1A2 (0.44) | DYRK1ANPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL10271446 | 0.80 | CYP1A2 (0.42) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL10220200 | 0.78 | KDM4E (0.41) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL10271289 | 0.77 | KDM4E (0.38) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8142323 | 0.74 | RAB9A (0.42) | NPC1RAB9ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL15178663 | 0.74 | RAB9A (0.42) | DYRK1ANPC1RAB9ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SEQUOIA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182854-A1 | HCV PROTEASE INHIBITORS | SERPINB1, CTSC, HPN | CYP2D6 1789/4885CLK1 2120/4885CDK5 810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.