Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 6/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12985402 | 0.88 | CXCL8 (0.53) | CXCL8HRH1CARM1PRMT1AKR1B1 | |
| SCHEMBL11389529 | 0.81 | HRH1 (0.65) | CXCL8HRH1 | |
| Hydrochloric Acid SCHEMBL11402907 | 0.80 | HRH1 (0.63) | CXCL8HRH1 | |
| SCHEMBL899883 | 0.79 | HRH1 (0.66) | CXCL8HRH1CHRM1 | |
| SCHEMBL10793404 | 0.78 | EPHX2 (0.48) | — | |
| SCHEMBL10793407 | 0.78 | EPHX2 (0.48) | — | |
| SCHEMBL3405256 | 0.77 | THRA (0.56) | HRH1CARM1PRMT1 | |
| SCHEMBL7882768 | 0.75 | CARM1 (0.48) | HRH1CARM1PRMT1 | |
| SCHEMBL23881810 | 0.74 | CARM1 (0.50) | HRH1CARM1PRMT1 | |
| SCHEMBL3407088 | 0.74 | FFAR4 (0.50) | HRH1CARM1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627358-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | Koninklijke Philips Electronics N.V. (NL) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049624-A1 | PRETARGETING KIT, METHOD AND AGENTS USED THEREIN | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-04-19 | — | — | WO | disclosed |