SCHEMBL12468912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20189793	0.84	POLB (0.62)	POLBGRM5CYP3A4KDM4EL3MBTL1
	SCHEMBL26872446	0.83	CYP11B2 (0.58)	POLBGRM5KDM4EL3MBTL1NPC1
	SCHEMBL20766926	0.83	MAPT (0.65)	POLBGRM5CYP3A4KDM4EL3MBTL1
	SCHEMBL20189462	0.83	POLB (0.56)	POLBGRM5CYP3A4KDM4EL3MBTL1
	SCHEMBL3831832	0.82	JAK2 (0.61)	POLBJAK2TYK2JAK1CYP3A4
	SCHEMBL30077014	0.82	JAK2 (0.61)	POLBJAK2TYK2JAK1CYP3A4
	SCHEMBL17152729	0.82	SMN1; SMN2 (0.56)	POLBGRM5NPC1RAB9ALMNA
	SCHEMBL20206201	0.81	POLB (0.58)	POLBGRM5CYP3A4KDM4EL3MBTL1
	SCHEMBL24021474	0.80	MAPT (0.56)	POLBGRM5TYK2CYP3A4KDM4E
	SCHEMBL20206158	0.80	POLB (0.53)	POLBGRM5CYP3A4KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.