Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246532 | 0.87 | CHAT (0.40) | CHATRAD52PKMHTTNPSR1 | |
| SCHEMBL16144030 | 0.82 | KDM4E (0.37) | CHATRAD52PKMHTTNPSR1 | |
| Iodide SCHEMBL3707094 | 0.82 | KDM4E (0.37) | CHATRAD52PKMHTTNPSR1 | |
| SCHEMBL18349245 | 0.77 | HTT (0.49) | CHATRAD52PKMHTTNPSR1 | |
| SCHEMBL1245824 | 0.77 | BACE1 (0.46) | CHATRAD52PKMHTTNPSR1 | |
| SCHEMBL19860018 | 0.76 | HTT (0.48) | CHATRAD52PKMHTTNPSR1 | |
| SCHEMBL1245835 | 0.72 | CHAT (0.59) | CHATRAD52PKMHTTNPSR1 | |
| Hydrochloric Acid SCHEMBL1246670 | 0.71 | CHAT (0.57) | CHATRAD52PKMHTTNPSR1 | |
| Beta-Alanine SCHEMBL1246610 | 0.70 | ATG4B (0.60) | HTTNPSR1MEN1NPC1POLB | |
| SCHEMBL1246527 | 0.70 | MAPT (0.42) | CHATRAD52PKMHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459734-A2 | NOVEL PEPTIDASE SUBSTRATES | Biomérieux (FR) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012809-A2 | NOVEL PEPTIDASE SUBSTRATES | bioMérieux (FR) | 2011-02-03 | — | — | WO | disclosed |