Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18349245 | 0.90 | HTT (0.49) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL20285887 | 0.84 | MEN1 (0.69) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL1246908 | 0.76 | CHAT (0.42) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL15294998 | 0.76 | POLB (0.52) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL16663902 | 0.74 | MEN1 (0.71) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL1246532 | 0.71 | CHAT (0.40) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL9455035 | 0.70 | MEN1 (0.70) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL9455038 | 0.70 | MEN1 (0.70) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL1245824 | 0.70 | BACE1 (0.46) | HTTKMT2AMEN1NPC1NSD2 | |
| SCHEMBL1245866 | 0.70 | LTA4H (0.45) | HTTKMT2AMEN1NPC1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890187-B2 | Prototype systems of theranostic biomarkers for in vivo molecular management of cancer | EPOS-IASIS RESEARCH AND DEVELOPMENT, LTD. (CY) | 2018-02-13 | — | — | US | disclosed |