SCHEMBL12469124

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12468994	1.00	NAMPT (0.39)	NAMPTHSD11B1FLT3PRKCQIRAK4
	SCHEMBL12469060	0.95	FLT3 (0.42)	HSD11B1FLT3PRKCQIRAK4MAPKAPK2
	SCHEMBL12469347	0.83	HSD11B1 (0.42)	HSD11B1PRKCQIRAK4
	SCHEMBL12685434	0.83	HSD11B1 (0.41)	HSD11B1PRKCQIRAK4CA12CA1
	SCHEMBL12685439	0.83	HSD11B1 (0.41)	HSD11B1PRKCQIRAK4CA12CA1
	SCHEMBL12469102	0.83	HSD11B1 (0.41)	HSD11B1PRKCQIRAK4CA12CA1
	SCHEMBL30077102	0.78	IRAK4 (0.47)	HSD11B1PRKCQIRAK4MAPKAPK2
	SCHEMBL12685236	0.78	IRAK4 (0.47)	HSD11B1PRKCQIRAK4MAPKAPK2
	SCHEMBL12685279	0.76	PRKCQ (0.56)	NAMPTHSD11B1PRKCQIRAK4
	SCHEMBL12685134	0.75	IRAK4 (0.56)	HSD11B1PRKCQIRAK4MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.