Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12469532 | 0.83 | BTK (0.42) | BTKFLT3KDRBRD4PIM1 | |
| SCHEMBL12469700 | 0.82 | BTK (0.40) | BTKFLT3KDRPIM1PIM2 | |
| SCHEMBL12469667 | 0.82 | BTK (0.43) | BTKFLT3PIM1PIM2GRM2 | |
| SCHEMBL12469409 | 0.82 | BTK (0.43) | BTKFLT3KDRBRD4PIM1 | |
| SCHEMBL12469665 | 0.82 | BTK (0.46) | BTKFLT3KDRPIM1PIM2 | |
| SCHEMBL12469863 | 0.82 | BTK (0.42) | BTKFLT3PIM1PIM2GRM2 | |
| SCHEMBL12469609 | 0.81 | BTK (0.39) | BTKFLT3KDRCSF1RGRM2 | |
| SCHEMBL12469588 | 0.80 | BTK (0.43) | BTKFLT3PIM1PIM2CSF1R | |
| SCHEMBL12469585 | 0.80 | BTK (0.45) | BTKFLT3CSF1RPDE7A | |
| SCHEMBL12469427 | 0.80 | BTK (0.67) | BTKFLT3KDRPIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047017-A2 | 2,3-DIHYDRO-ISOINDOL-1-ONE DERIVATIVE AND A COMPOSITION COMPRISING THE SAME | 크리스탈지노믹스(주) (KR) | 2012-04-12 | — | — | WO | disclosed |