Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL239565 | 1.00 | KMT2A (0.36) | KMT2AALDH1A1LMNAPKMGAA | |
| SCHEMBL240708 | 0.82 | SMN1; SMN2 (0.34) | KMT2AALDH1A1LMNAPKMGAA | |
| SCHEMBL241050 | 0.81 | MAPT (0.42) | KMT2AALDH1A1LMNAGAAMAPT | |
| SCHEMBL239694 | 0.79 | MAPT (0.36) | KMT2AALDH1A1LMNAGAAMAPT | |
| SCHEMBL240689 | 0.79 | ALDH1A1 (0.36) | KMT2AALDH1A1LMNAPKMGAA | |
| SCHEMBL239658 | 0.78 | KMT2A (0.43) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL12469738 | 0.78 | KMT2A (0.43) | KMT2AALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL240878 | 0.76 | KAT2B (0.42) | KMT2AALDH1A1LMNAPKMGAA | |
| SCHEMBL240751 | 0.76 | SMN1; SMN2 (0.42) | KMT2AALDH1A1LMNAPKMGAA | |
| SCHEMBL238882 | 0.75 | KAT2B (0.41) | KMT2AALDH1A1LMNAPKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2678334-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-2627651-A1 | ANTI-VIRAL COMPOUNDS | Abbvie Inc. (US) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012116257-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. (US) | 2012-08-30 | — | — | WO | disclosed |
| WO-2012051361-A1 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2012-04-19 | — | — | WO | disclosed |