Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CBFB | Q13951 | 4/20 | 0.41 |
| ▸ | METAP1 | P53582 | 6/20 | 0.41 |
| ▸ | METAP2 | P50579 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619864 | 0.90 | PDPK1 (0.44) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL19691749 | 0.81 | CBFB (0.49) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL18091913 | 0.79 | F2 (0.43) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL11303973 | 0.77 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL535052 | 0.77 | PDE5A (0.44) | SMN1; SMN2NPC1RAB9APKMHSD17B10 | |
| SCHEMBL3327100 | 0.75 | KDM4E (0.49) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL8311607 | 0.74 | KDM4E (0.56) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| Dipyridyl SCHEMBL9115752 | 0.74 | KDM4E (0.56) | SMN1; SMN2NPC1RAB9ATDP1PKM | |
| SCHEMBL29008471 | 0.74 | TSHR (0.37) | NPC1RAB9ATDP1ALOX15LMNA | |
| Carbamic Acid SCHEMBL7648295 | 0.73 | PDE4B (0.39) | SMN1; SMN2NPC1RAB9ATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2627649-A1 | CXCR4 RECEPTOR ANTAGONISTS | Proximagen Limited (GB) | 2013-08-21 | — | — | EP | disclosed |
| WO-2012049277-A1 | CXCR4 RECEPTOR ANTAGONISTS | PROXIMAGEN LTD (GB) | 2012-04-19 | — | — | WO | disclosed |