Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843948 | 0.90 | KCNH2 (0.41) | PDE5APDE3BPDE3ANPC1RAB9A | |
| SCHEMBL3005573 | 0.88 | KCNH2 (0.47) | PDE5APDE3BPDE3ASMN1; SMN2TP53 | |
| SCHEMBL2780530 | 0.87 | POLB (0.41) | PDE5APDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL29629123 | 0.87 | KCNH2 (0.50) | SMN1; SMN2TP53ADORA3ADORA2AMAPT | |
| SCHEMBL8973267 | 0.87 | KCNH2 (0.50) | SMN1; SMN2TP53ADORA3ADORA2AMAPT | |
| SCHEMBL27724619 | 0.87 | KCNH2 (0.50) | SMN1; SMN2TP53ADORA3ADORA2AMAPT | |
| SCHEMBL30670275 | 0.85 | MTOR (0.38) | PDE5APDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL24088760 | 0.83 | NPC1 (0.45) | CTSKKDM4EHPGDNPC1RAB9A | |
| SCHEMBL13115362 | 0.83 | NPC1 (0.42) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL1436268 | 0.82 | LOXL2 (0.40) | CTSKKDM4EALDH1A1HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108554456-A | A kind of application of rare earth imidazole salt compound as catalyst | 苏州大学 | 2018-09-21 | — | — | CN | disclosed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | disclosed |
| EP-1952918-B1 | METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | TOYO INK MFG CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-8440110-B2 | Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film | TOYO INK MFG CO., LTD. (JP) | 2013-05-14 | — | — | US | disclosed |
| CN-101287566-B | Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film | TOYO INK MFG CO | 2012-05-23 | — | — | CN | disclosed |
| EP-1990377-B1 | COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT | TOYO ALUMINIUM KK (JP) | 2012-02-08 | — | — | EP | disclosed |
| CN-101384674-B | Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation comprising said colored metallic pigment | TOYO ALUMINIUM KABUSHIKI KAISHA (JP) | 2011-12-28 | — | — | CN | disclosed |
| US-7998266-B2 | Colored metallic pigment, process for producing the same, and coating composition and cosmetic preparation containing said colored metallic pigment | TOYO ALUMINIUM KABUSHIKI KAISHA (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20110175040-A1 | METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | TOYO INK MFG CO., LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| US-7981327-B2 | Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film | TOYO INK MFG. CO. LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20090017082-A1 | COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION CONTAINING SAID COLORED METALLIC PIGMENT | TOYO ALUMINIUM KABUSHIKI KAISHA (JP) | 2009-01-15 | — | — | US | disclosed |
| EP-1990377-A1 | COLORED METALLIC PIGMENT, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION AND COSMETIC PREPARATION COMPRISING SAID COLORED METALLIC PIGMENT | TOYO ALUMINIUM KABUSHIKI KAISHA (JP) | 2008-11-12 | — | — | EP | disclosed |
| CN-101287566-A | Method for producing metal microparticle dispersion, conductive ink using metal microparticle dispersion produced by the method, and conductive coating film | TOYO INK MFG CO (JP) | 2008-10-15 | — | — | CN | disclosed |
| EP-1952918-A1 | METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | Toyo Ink Mfg. Co., Ltd (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | disclosed |
| US-6492377-B1 | Imidazotriazolopyrimidines with adenosine-antagonistic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-0585014-B1 | Process for the preparation of 2-(un)substituted 4-alkylimidazoles | SHIONOGI & CO (JP) | 2000-02-23 | — | — | EP | disclosed |
| CN-1091130-A | The preparation of imidazoles | SHIONOGI & CO (JP) | 1994-08-24 | — | — | CN | disclosed |
| US-5312927-A | Preparation of imidazoles | SHIONOGI & CO., INC. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0585014-A2 | Process for the preparation of 2,5-disubstituted imidazoles | SHIONOGI & CO., LTD. (JP) | 1994-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | MRPL38, CXCL8, ALG8 | PDE5A 3337/4885PDE3B 3866/4885PDE3A 3801/4885 |
| US-20080146569-A1 | Nicotinamide Derivatives | NNT, NAMPT, NADK | PDE5A 404/4885PDE3B 359/4885PDE3A 475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.