SCHEMBL12469844

SCHEMBL12469844

c1ccc(-c2ccccc2-c2ccc[nH]2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.44
KDR P35968 2/20 0.41
AURKA O14965 1/20 0.41
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
CYP2A6 P11509 1/20 0.39
MAPK1 P28482 1/20 0.39
MAPT P10636 1/20 0.38
DCUN1D1 Q96GG9 2/20 0.37
NISCH Q9Y2I1 1/20 0.37
PTGS2 P35354 1/20 0.36
PARP1 P09874 1/20 0.36
ADRA1D P25100 1/20 0.36
ADRA1A P35348 1/20 0.36
ADRA1B P35368 1/20 0.36
CSF1R P07333 2/20 0.36
IKBKB O14920 1/20 0.36
CHUK O15111 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21858016 0.89 MAPT (0.46) ADORA2AKDRAURKAALDH1A1HSD17B10
SCHEMBL15416821 0.88 KDR (0.47) ADORA2AKDRAURKAPARP1ADRA1D
SCHEMBL80142 0.80 HDAC1 (0.48) ADORA2AALDH1A1MAPTNISCHCSF1R
SCHEMBL28367707 0.79 HDAC7 (0.41) ADORA2AALDH1A1HSD17B10HPGDMAPT
SCHEMBL31160467 0.79 HDAC7 (0.41) ADORA2AALDH1A1HSD17B10HPGDMAPT
SCHEMBL8780008 0.79 PTGS2 (0.40) KDRAURKANISCHPTGS2
Fluoride SCHEMBL30394298 0.78 HDAC1 (0.47) ADORA2AKDRALDH1A1MAPTNISCH
SCHEMBL28212557 0.78 HDAC1 (0.47) ADORA2AKDRALDH1A1MAPTNISCH
SCHEMBL27882289 0.78 HDAC1 (0.47) ADORA2AKDRALDH1A1MAPTNISCH
SCHEMBL27515517 0.78 HDAC1 (0.47) ADORA2AKDRALDH1A1MAPTNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114656654-B Modified lignin self-repairing conductive hydrogel and preparation method and application thereof 江苏理工学院 2023-07-11 CN disclosed
EP-2627732-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES Merck Patent GmbH (DE) 2013-08-21 EP disclosed
US-20130150576-A1 NITROGEN-CONTAINING AROMATIC COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2013-06-13 US disclosed
WO-2012048900-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. . (DE) 2012-04-19 WO disclosed