SCHEMBL28367707

SCHEMBL28367707

Cc1ccc(-c2ccccc2)c(-c2ccc[nH]2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC7 Q8WUI4 1/20 0.41
ADORA2A P29274 1/20 0.40
PSMB5 P28074 1/20 0.39
ELANE P08246 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
PIM1 P11309 1/20 0.37
METAP2 P50579 1/20 0.37
ESR2 Q92731 1/20 0.37
MAPT P10636 3/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 3/20 0.36
NPC1 O15118 2/20 0.36
TP53 P04637 2/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MAOB P27338 1/20 0.36
NUDT1 P36639 1/20 0.36
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31160467 0.93 HDAC7 (0.41) HDAC7ADORA2APSMB5ELANEPTGDR2
SCHEMBL12469844 0.79 ADORA2A (0.44) ADORA2AMAPTHPGDHSD17B10ALDH1A1
SCHEMBL3005820 0.79 ELANE (0.52) HDAC7PSMB5ELANEPTGDR2METAP2
SCHEMBL6285309 0.78 MAPT (0.50) ELANEMAPTKDM4ELMNANPC1
SCHEMBL8056200 0.77 ELANE (0.50) HDAC7PSMB5ELANEPTGDR2METAP2
Hydrogen Sulfide SCHEMBL27603601 0.77 ELANE (0.50) HDAC7PSMB5ELANEPTGDR2METAP2
SCHEMBL29280157 0.77 ALOX15 (0.47) MAPTKDM4ELMNANPC1TP53
SCHEMBL29280165 0.75 IDO1 (0.57) PIM1MAPTKDM4ELMNANPC1
Lithium SCHEMBL31260751 0.73 ELANE (0.50) HDAC7PSMB5ELANEPTGDR2METAP2
SCHEMBL15416944 0.73 CDK2 (0.47) ADORA2AKDM4ENPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115884812-A Cleaning composition 株式会社资生堂 2023-03-31 CN disclosed
CN-115461030-A Cleaning agent composition 株式会社资生堂 2022-12-09 CN disclosed
CN-115279332-A Composition containing lamellar gel, emulsified composition and external composition for skin 株式会社资生堂 2022-11-01 CN disclosed
CN-115151239-A Oil-in-water type emulsion composition 株式会社资生堂 2022-10-04 CN disclosed
CN-114846108-A Anti-pollution material 日产化学株式会社 2022-08-02 CN disclosed
CN-114466647-A Solid water-in-oil type emulsion cosmetic 株式会社资生堂 2022-05-10 CN disclosed
CN-113873996-A Personal care compositions and malodor suppression methods 株式会社资生堂 2021-12-31 CN disclosed
CN-113329794-A Skin external preparation and method for improving ultraviolet protection effect 株式会社资生堂 2021-08-31 CN disclosed
CN-113286635-A Sunscreen cosmetic 株式会社资生堂 2021-08-20 CN disclosed
CN-113164794-A Emulsified cosmetic composition 株式会社资生堂 2021-07-23 CN disclosed
CN-113143780-A Thickening composition containing lipopeptide-type compound 日产化学工业株式会社 2021-07-23 CN disclosed
CN-113015559-A Cosmetic preparation 株式会社资生堂 2021-06-22 CN disclosed
CN-112996473-A Powder dispersion composition and dispersion method thereof 株式会社资生堂 2021-06-18 CN disclosed
CN-112891245-A Stick-shaped base material containing lipid peptide type compound 日产化学工业株式会社 2021-06-04 CN disclosed
CN-112714643-A Water-in-oil type composition for external application to skin 株式会社资生堂 2021-04-27 CN disclosed
CN-112672729-A Water-in-oil type emulsion cosmetic 株式会社资生堂 2021-04-16 CN disclosed
CN-112638359-A Composition for forming coating film 日产化学株式会社 2021-04-09 CN disclosed
CN-112638355-A Cosmetic and cleaning product 株式会社资生堂 2021-04-09 CN disclosed
CN-111565703-A Composition containing powder 日产化学株式会社 2020-08-21 CN disclosed
CN-106572957-B Skin color improving agent and composition for improving skin color 昭和电工株式会社 2020-03-27 CN disclosed