Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | GCG | P01275 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | BCR | P11274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28851926 | 0.81 | EPHX2 (0.39) | MBOAT4CYP46A1GCGGCGREPHX2 | |
| SCHEMBL17666286 | 0.79 | RXRA (0.38) | MBOAT4CYP46A1GCGGCGREPHX2 | |
| SCHEMBL16983155 | 0.76 | NOTUM (0.39) | CYP46A1EPHX2SLC34A1RXRAGRIN1 | |
| SCHEMBL29819715 | 0.74 | L3MBTL1 (0.44) | MBOAT4CYP46A1EPHX2RXRAGRIN1 | |
| SCHEMBL16753675 | 0.74 | L3MBTL1 (0.44) | MBOAT4CYP46A1EPHX2RXRAGRIN1 | |
| SCHEMBL17666300 | 0.73 | GCG (0.40) | CYP46A1GCGGCGREPHX2PDE10A | |
| SCHEMBL16983105 | 0.71 | GCG (0.39) | CYP46A1GCGGCGREPHX2RXRA | |
| SCHEMBL11900303 | 0.71 | EPHX2 (0.44) | CYP46A1GCGGCGREPHX2ABL1 | |
| SCHEMBL25843587 | 0.70 | HTR2A (0.36) | MBOAT4GCGGCGRPDE10AABL1 | |
| SCHEMBL11899948 | 0.69 | GCG (0.46) | GCGGCGRRXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673260-A1 | GLUCAGON RECEPTOR MODULATOR | Pfizer Inc (US) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107850-A1 | GLUCAGON RECEPTOR MODULATOR | PFIZER INC. (US) | 2012-08-16 | — | — | WO | disclosed |