SCHEMBL12470533

SCHEMBL12470533

c1ccc2nc(-c3ccc4ccc5ncccc5c4n3)ccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.64
CYP3A4 P08684 5/20 0.56
ALDH1A1 P00352 4/20 0.50
PDE10A Q9Y233 4/20 0.47
MAPT P10636 5/20 0.47
KDM4E B2RXH2 4/20 0.47
RAB9A P51151 5/20 0.45
NPC1 O15118 4/20 0.45
CYP2D6 P10635 3/20 0.45
CYP1A2 P05177 3/20 0.45
AR P10275 2/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
TP53 P04637 3/20 0.42
ALOX15 P16050 2/20 0.42
GMNN O75496 2/20 0.42
THPO P40225 2/20 0.42
PMP22 Q01453 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17598971 0.94 LMNA (0.74) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL29048206 0.92 LMNA (0.72) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL27681790 0.87 LMNA (0.73) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL4246178 0.85 LMNA (0.61) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL28996104 0.84 LMNA (0.64) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL29031195 0.84 LMNA (0.55) LMNACYP3A4ALDH1A1PDE10AMAPT
Quinoline SCHEMBL9104755 0.83 LMNA (0.85) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL28593151 0.83 KDM4E (0.59) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL27820373 0.83 LMNA (0.57) LMNACYP3A4ALDH1A1PDE10AMAPT
SCHEMBL669488 0.82 LMNA (0.61) LMNACYP3A4ALDH1A1PDE10AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8986436-B2 Luminescent pigments and their use in security applications Fábrica Nacional de Moneda y Timbre—Real Casa de la Moneda (ES) 2015-03-24 US claimed
EP-2673335-B1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NAC DE MONEDA Y TIMBRE REAL CASA DE LA MONEDA (ES) 2014-12-10 EP claimed
US-20140158019-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FABRICA NAIONAL DE MONEDA Y TIMBRE- REAL CASA DE LA MONEDA (ES) 2014-06-12 US claimed
EP-2673335-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS Fábrica Nacional de Moneda Y Timbre - Real Casa de la Moneda (ES) 2013-12-18 EP claimed
WO-2012107558-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NACIONAL DE MONEDA Y TIMBRE - REAL CASA DE LA MONEDA (ES) 2012-08-16 WO claimed
CN-109790191-B Platinum complexes and methods of use thereof 香港大学 2022-04-08 CN disclosed
CN-109790191-A Platinum complex and its application method 香港大学 2019-05-21 CN disclosed
WO-2018024172-A1 PLATINUM COMPLEXES AND METHODS OF USE THEREOF THE UNIVERSITY OF HONG KONG (CN) 2018-02-08 WO disclosed
US-8986436-B2 Luminescent pigments and their use in security applications Fábrica Nacional de Moneda y Timbre—Real Casa de la Moneda (ES) 2015-03-24 US disclosed
EP-2673335-B1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NAC DE MONEDA Y TIMBRE REAL CASA DE LA MONEDA (ES) 2014-12-10 EP disclosed
US-20140158019-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FABRICA NAIONAL DE MONEDA Y TIMBRE- REAL CASA DE LA MONEDA (ES) 2014-06-12 US disclosed
EP-2673335-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS Fábrica Nacional de Moneda Y Timbre - Real Casa de la Moneda (ES) 2013-12-18 EP disclosed
WO-2012107558-A1 LUMINESCENT PIGMENTS AND THEIR USE IN SECURITY APPLICATIONS FÁBRICA NACIONAL DE MONEDA Y TIMBRE - REAL CASA DE LA MONEDA (ES) 2012-08-16 WO disclosed