Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1246383 | 0.94 | SCN9A (0.51) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL3706752 | 0.87 | LPAR1 (0.45) | SCN9ASCN5AMAPTGAANPSR1 | |
| SCHEMBL1245184 | 0.85 | SCN9A (0.53) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL3707275 | 0.83 | LPAR1 (0.40) | SCN9ASCN5AMAPTGAANPSR1 | |
| SCHEMBL11896414 | 0.82 | LPAR1 (0.49) | SCN9ASCN5AMAPTGAANPSR1 | |
| SCHEMBL1247566 | 0.82 | SCN9A (0.59) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL1247206 | 0.81 | SCN9A (0.61) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL1245362 | 0.80 | SCN9A (0.57) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL1247179 | 0.80 | SCN9A (0.55) | SCN9ASCN5ANTRK1MAPTGAA | |
| SCHEMBL1246319 | 0.80 | SCN9A (0.53) | SCN9ASCN5ANTRK1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462128-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | claimed |
| WO-2011017350-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | claimed |