Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.34 |
| ▸ | HTR3B | O95264 | 3/20 | 0.34 |
| ▸ | HTR3A | P46098 | 3/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12471091 | 0.85 | MEN1 (0.42) | PTPN1PTPN2CXCR4ADORA2AADORA1 | |
| SCHEMBL2170258 | 0.84 | TLR8 (0.47) | MAPTALDH1A1LCKTLR7TLR8 | |
| SCHEMBL31653854 | 0.78 | PTPN1 (0.45) | PTPN1PTPN2ADORA2AADORA1MAPT | |
| SCHEMBL12403793 | 0.77 | TP53 (0.37) | PTPN1PTPN2CXCR4MAPTALDH1A1 | |
| SCHEMBL12324268 | 0.75 | APP (0.40) | PTPN1PTPN2CXCR4ALDH1A1TLR8 | |
| SCHEMBL12403800 | 0.74 | ALDH1A1 (0.34) | PTPN1PTPN2CXCR4MAPTALDH1A1 | |
| SCHEMBL2164490 | 0.72 | MAPK8 (0.37) | PTPN1PTPN2ALDH1A1NPSR1LCK | |
| SCHEMBL484125 | 0.71 | APP (0.46) | ADORA2AMAPTALDH1A1KDM4ERAD51 | |
| SCHEMBL12323637 | 0.71 | TOP2A (0.37) | MAPTALDH1A1NPSR1LCKKDM4E | |
| SCHEMBL12323634 | 0.70 | APP (0.51) | ADORA2AADORA1MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182812-A1 | Imaging Agents for Detecting Neurological Disorders | MAPT, APP, PSEN1 | PTPN1 4822/4885PTPN2 4809/4885CXCR4 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.