Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 12/20 | 0.82 |
| ▸ | NPC1 | O15118 | 7/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | MMP2 | P08253 | 4/20 | 0.68 |
| ▸ | MMP9 | P14780 | 4/20 | 0.68 |
| ▸ | MMP8 | P22894 | 4/20 | 0.68 |
| ▸ | MMP13 | P45452 | 3/20 | 0.68 |
| ▸ | CASP3 | P42574 | 2/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566197 | 0.93 | NPC1 (0.78) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL17898258 | 0.90 | NPBWR1 (1.00) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL31049578 | 0.90 | NPBWR1 (1.00) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL3193088 | 0.87 | NPBWR1 (0.80) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL3183535 | 0.87 | MAPT (0.66) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL28612020 | 0.87 | MMP2 (0.71) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL10172964 | 0.87 | NPBWR1 (0.80) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL13856173 | 0.87 | NPBWR1 (0.80) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL2308775 | 0.87 | NPBWR1 (0.79) | NPBWR1NPC1MAPTRAB9AHTT | |
| SCHEMBL20982681 | 0.87 | NPC1 (0.73) | NPBWR1NPC1MAPTRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118619886-B | Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof | 山东齐氟新材料有限公司 | 2024-10-25 | — | — | CN | claimed |
| CN-118619886-A | Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof | 山东齐氟新材料有限公司 | 2024-09-10 | — | — | CN | claimed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | claimed |
| CN-118619886-B | Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof | 山东齐氟新材料有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-118619886-A | Bisbenzimidazole phenoxy alkyl diamine compound and preparation method and application thereof | 山东齐氟新材料有限公司 | 2024-09-10 | — | — | CN | disclosed |
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PUSAN NAT UNIV IND COOP FOUND (KR) | 2015-12-24 | — | — | US | disclosed |
| US-9155690-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof | PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) | 2015-10-13 | — | — | US | disclosed |
| US-8889881-B2 | Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor | Pusan National University Industry —University Cooperation Foundation (KR) | 2014-11-18 | — | — | US | disclosed |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | Pusan National University Indusrtyuniversity (KR) | 2014-02-06 | — | — | US | disclosed |
| WO-2012108689-A2 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | 부산대학교 산학협력단 (KR) | 2012-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366776-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF | PPARG, PPARA, TYR | NPBWR1 1705/4885NPC1 3522/4885MAPT 1956/4885 |
| US-20140037564-A1 | NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR | PPARG, PPARA, PPARD | NPBWR1 1193/4885NPC1 3207/4885MAPT 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.