Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473283 | 0.89 | ALDH1A1 (0.38) | PDE4DMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12473402 | 0.85 | NPC1 (0.41) | KMT2AALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL12473403 | 0.83 | BCHE (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473364 | 0.82 | PRMT7 (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473436 | 0.82 | PRMT7 (0.35) | PDE4DMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12473398 | 0.82 | PDE10A (0.37) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473361 | 0.82 | PRMT7 (0.33) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473314 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473287 | 0.80 | KMT2A (0.35) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL12473438 | 0.80 | F2RL3 (0.33) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |